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Sacks, and Kosali I
This review article examines the translational evolution of glucagon-like peptide-1 receptor agonists (GLP-1RAs), tracing their progression from the discovery of exendin-4 in Gila monster venom to long-acting peptide analogues and the first orally delivered peptide therapy, oral semaglutide

The global Obesity Medicines market reached $66 billion in list price sales value in 2025, according to IQVIAs ForecastLink, and is forecast to rise to $92 billion in 2026, before reaching between $105 billion and $200 billion by 2027 and beyond
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