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This is why fueling strategy matters so much during GLP-1 therapy

15 In a large meta-analysis of recent cardiovascular outcome trials, GLP-1 RAs were reported to reduce the risk of stroke significantly in people with T2D compared with placebo (hazard ratio [HR], 0.83 [95% CI, 0.760.92]

Data heterogeneity and sensitivity analysis Heterogeneity is a common issue in meta-analyses, arising from differences in study design, patient characteristics, interventions and outcome measures among included studies

Key highlights A biweekly or every other week dosing schedule is becoming popular as an off-label maintenance strategy to sustain weight loss and metabolic benefits

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