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The medication requires dose titration over several weeks to minimize gastrointestinal adverse effects, which are the most commonly reported side effects

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To combat this, the General Pharmaceutical Council set out guidance in September 2024 that said pharmacies must: Not rely solely on an online questionnaire but use two-way communication between patient and prescriber

Rheumatoid arthritis is a chronic autoimmune condition driven by immune overactivation and systemic inflammation, and meaningful improvement often requires addressing its root causes

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