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Nevertheless, bone consequences of intentional weight loss interventions in PwO are well known: (i) significant weight loss induced by caloric restriction and bariatric surgery results in accelerated bone turnover and bone loss, and (ii) unlike caloric restriction interventions, PwO experience a substantial deterioration in bone microarchitecture and strength associated with an increased risk of fracture after bariatric surgery especially malabsorptive procedures

Read this article if you want to lose weight with semaglutide but are intimidated by reports of how expensive it is

Some commonly used GLP-1 receptor agonists include exenatide, liraglutide, and dulaglutide