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Description
16 Joint & Musculoskeletal Pain Overweight and obesity have a profound impact on overall physical function, musculoskeletal pain and both the development and progression of osteoarthritis

P., Slade, E., Ventura, A

In individuals with obesity or metabolic dysfunction, this hormonal signaling system often does not function optimally, leading to persistent hunger, frequent cravings, and difficulty achieving satiety even after eating adequate meals

Historical Context: The Arc of Evidence Earlier studies had already hinted at safety

3 Insulin resistance in type 1 diabetes Insulin resistance is associated with micro- and macrovascular complications in patients with T1D (28)
