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Notwithstanding, the impact of public health initiatives has been less pronounced in minority groups and persons with mental disorders wherein the rates of smoking remain higher (e.g., 4080% smoking rates amongst persons with depressive, bipolar and psychotic disorders) [29]

The first studyperformed by our groupis a randomized, doubleblinded, placebocontrolled clinical trial investigating reduction in heavy drinking days after treatment with exenatide once weekly for 26 weeks in patients diagnosed with AUD

According to available research, the two most effective licensed treatments available currently are Wegovy and Mounjaro

Separate estimates suggest around 10 million Americans were on GLP-1 treatment in 2025, with JP Morgan projecting 25 million by 2030

Scientific Evidence: Do Berberine Patches Actually Work