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The trial, which was randomized, double-blinded, and placebo-controlled, was conducted at the Mental Health Center Copenhagen

Other significant safety considerations include a history of pancreatitis, acute kidney injury risk, diabetic retinopathy complications in patients with type 2 diabetes, gallbladder disease, hypoglycemia risk in patients using other diabetes medications, and mental health monitoring for mood changes or suicidal ideation

Toward a broader response to cardiometabolic disease

with a BMI of 30 or more and heart failure with preserved ejection fraction, uncontrolled hypertension, or chronic kidney disease stage 3a or above

doi: 10.1007/s00394-016-1188-y