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Akkermansia muciniphila produces P9, a small protein that interacts with intercellular adhesion molecule 2 to increase thermogenesis and glucagon-like peptide-1 secretion in mice.

Currently, the Food and Drug Administration (FDA) has approved seven GLP-1 prescription medications:GENERIC NAMEBRAND NAMEFORMSSemaglutideOzempicRybelsusWegovyInjectionOral PillTirzepatideMounjaroZepboundInjectionLiraglutideVictozaSaxendaInjectionDulaglutideTrulicityInjectionExenatideByettaInjectionLixisenatideAdlyxinInjectionOrforglipron*Foundayo*Oral Pill*Non-peptide, small molecule When used in addition to a reduced calorie diet and increased physical activity, these medications are FDA approved for one or more of the following:Improving blood sugar levels in adults with T2D.Reducing excess body weight and keep it off long term in:Adults and children aged 12 years and older with obesity.Adults who are overweight who also have at least one weight-related medical problem (such as high blood pressure, diabetes, or high cholesterol)Reducing the risk of major adverse cardiovascular events in adults with T2D who have heart disease or are at high risk for these events.Can Service Members use GLP-1 prescription medications?GLP-1 medications are only available with a prescription from a qualified healthcare provider

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