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What It Doesnt Prove The researchers and outside experts have been careful to note the studys limitations

Chang et al

Effects on body weight DPP-4 inhibitors are weight-neutral, and thus they may be an attractive option for some patients if other options would likely cause additional weight gain

Case in point: In a study of 121 subjects, researchers found that those who took 14 grams of allulose a day had a statistically significant decrease in body mass index (BMI), abdominal, and subcutaneous fat compared to those who took a placebo, though absolute losses were small (around .75% of body fat)

The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial