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First escalation (5 mg): weeks 5 through 8 The jump from 2.5 mg to 5 mg is where many researchers first encounter meaningful side effects
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Tirzepatide and semaglutide work similarly, but tirzepatide targets both GIP and GLP-1 receptors, while semaglutide primarily targets GLP-1 alone
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doi: 10.2337/db22-727-P 88 ChavdaVPAjabiyaJTeliDBojarskaJApostolopoulosV
