allodynia glp 1 Therapeutic Effects of GLP-1 Receptor Agonists and DPP-4 Inhibitors in Neuropathic Pain: Mechanisms and Clinical Implications GLP-1 Side Effect Relief –

Preliminary program results are promising: ~1,500 clients have enrolled in the program since the program launched in April 2023, including: 61% of commercial employer-sponsored lives 17% of commercial health plan lives ** 67% of members meet smart logic criteria and do not require submission of a PA request 84% of PA requests result in denial, and 72% overall target fill rate *** ~$1B or ~$4.86 PMPM in client savings 3 These drugs are being studied in both weight- and non-weight-related conditions

GLP-1 agonists are a class of medications that mimic hormones in the body to help regulate blood sugar and appetite

(ii) risk of mispricing or improper valuation

Consistency matters enormously with GLP-1 therapy because steady blood levels produce better results than erratic dosing

Hormonal therapy interactions Patients combining tirzepatide with hormone replacement therapy represent a significant and growing population