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Key Industry Developments: In October 2025 , Eli Lilly and Company achieved its fourth Phase III success with its oral GLP-1 receptor agonist, orforglipron, in type 2 diabetes trials

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For many patients, taste changes are most noticeable during the initial weeks of treatment or following dose increases , often coinciding with the period when gastrointestinal adverse effects such as nausea are most prominent

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Histology 53 (5), 793804