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Final Thoughts GLP-1 medications have transformed how we treat obesity: Semaglutide broke ground with ~15% average weight loss

Once a drug is approved by the FDA, it is continuously monitored to ensure that it remains safe for public use

Some studies show that moderate increase of cortisol over long periods can lead to reduced immune function, obesity, pre-diabetes, reduced memory and even heart diseases

Mechanical Load and GLP-1 Exercise Skeletal muscle depends on mechanical stress for its growth and maintenance a principle known as mechanotransduction

The latest International Diabetes Federation (IDF) report indicates a 10.5% prevalence of T2DM in adults in 2021, projected to reach 12.2% by 2045 (Sun et al., 2022