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Description
The impact of Wegovy on the Medicare population may not be as significant as the impact commercial payers have seen when choosing to cover Wegovy, given the concomitant prevalence of diabetes and overweight/obesity in Americans over age 65

Why this matters: First oral GLP-1 for weight management, reducing the injection barrier Strong clinical evidence from the OASIS 4 trial, showing ~16.6% average weight loss with adherence and improvements in cardiovascular risk factors Broader reach ahead, with U.S

Gut Microbes , 11(4), 855866

With rapid adoption rates, ongoing innovations (including oral GLP-1 options now entering the market), and sustained consumer interest, the impact on medical aesthetics will continue through 2026 and beyond

78 In the DURATION trial, a similar finding was made in which patients administered with exenatide once weekly than liraglutide reported higher incidences of nodules at the injection, pruritus at the injection site, and erythema at the injection site
