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Mitochondrial dysfunction, characterized by impaired -oxidation capacity and increased ROS formation, fuels the aberrant ROS production [137]

[53] reported a significant reduction in the resting energy expenditure after SG and a significant degree of metabolic adaptation

Side effects of orlistat can be unpleasant: oily spotting, gas, stomach pain, fecal urgency or incontinence, soft stools, and the possibility of serious liver injury can occur
