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GLP-1s greatest effectiveness comes when theyre part of a comprehensive approach to weight care that includes medical, nutritional and behavioral support, Kumar explains

This is exactly why dual diagnosis treatment matters so much

monitor patients for the emergence or worsening of depression, suicidal thoughts or behavior, and any unusual changes in moods or behaviors

So how did we get from GLP-1 for diabetes to GLP-1 for weight loss

"The ability to have active management to overweight companies that are actually in market producing the drugs and then go down the line to identify those that are in particular phases is powerful," Mazza told CNBC's "ETF Edge" last Monday