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[27] Unlike many other antioxidants, melatonin can cross cellular membranes freely and access intracellular compartments, including mitochondria, where it may help protect against oxidative damage

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Doubling your dose will not accelerate resultsit will only trigger hospitalization-level complications

However, this equation includes a race coefficient that may overestimate eGFR in non-Hispanic Black individuals and underestimate CKD prevalence compared with the newer CKD-EPI 2021 equation, which removes race adjustment and is recommended by current KDIGO guidelines