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The picture is not as simple as "semaglutide causes blood clots." It is more accurate to say that semaglutide appears to shift certain cardiovascular risks in different directions simultaneously
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Another DPP4 inhibitor Des-fluoro-sitagliptin was also reported to decrease the accumulation of M1 macrophages in Gck +/- mice, a -cellspecific glucokinase haploinsufficient (Gck+/) diabetic model (33)
Semaglutide works by slowing stomach emptying and signaling fullness to your brain, which is why consistent weekly dosing produces better results than split doses

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