glp-1 news 2025 november ISPOR 2025: Exploring reasons for discontinuation Side Effects: Endocrine Society Journals
Description
A one-day-early injection of 2.4 mg creates a more noticeable spike
Thyroid C-Cell Tumors: In mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)
Let's break it down
Clinical trials stop after a few years, and some of the currently FDA-approved drugs have only been around for a couple of years
Also, 93.5% of the people who took GLP-1s survived during the five-year follow-up, versus 85.7% of those who didnt take GLP-1s
