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We aimed to systematically retrieve all currently available RCTs of tirzepatide in individuals with type 2 diabetes and synthesise the evidence by means of clinically relevant meta-analyses for outcomes of efficacy and safety
doi: 10.1523/jneurosci.0798-17.2017
Crucially, its formulation allows it to be taken any time of the day without the food or water restrictions that can complicate other oral therapies
57 In summary, evidence for the BP benefits of GLP-1RAs mainly comes from experimental studies on patients with T2D and obesity, clarifying potential biological mechanisms for this effect
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