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So theres often an interplay between the medications effects and the patients behavioral response

This should include: TSH Free T4 and free T3 Reverse T3 Thyroid peroxidase (TPO) antibodies (to assess for autoimmune Hashimotos thyroid disease) Iron, ferritin, vitamin B12, vitamin D, and selenium levels Thyroid dysfunction frequently co-occurs with metabolic diseases such as type 2 diabetes and obesity, and optimizing thyroid status is crucial for overall metabolic health

However, based on the release of newer agents over the recent past, some have suggested that the modern approach to disease management should be based upon identification of its etiology and correcting the underlying biological disturbances

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Aging 12(9):86408651 Chen J, Xu S, Zhou W, Wu L, Wang L, Li W (2020) Exendin-4 reduces ventricular arrhythmia activity and calcium sparks-mediated sarcoplasmic reticulum Ca leak in rats with heart failure