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Description
Older adults face the steepest cliff

Semaglutide reduces major adverse cardiovascular events, heart failure composite, cardiovascular death, and all-cause death in patients with atherosclerotic cardiovascular disease and overweight or obesity and heart failure

Methods We included a population of people with a first-time GLP-1 RA prescription between January 2018 and October 2024

Longer duration: The week-long half-life means receptors are consistently activated rather than experiencing daily fluctuation
Gastroenterology 142:4654.e42