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Additionally, improved insulin sensitivity from initial weight loss can decrease the medication's effect on appetite and blood sugar control

Certain forms of semaglutide are also used for chronic weight management in adults with obesity or in overweight adults who have weight-related medical problems

Compounded GLP-1 Therapies Compounded medications: Are not FDA-approved Do not undergo FDA premarket review for safety, effectiveness, or manufacturing quality May only be prepared when a licensed prescriber determines there is a clinically significant difference needed for an identified patient Compounded medications are not FDA-approved and do not undergo FDA review for safety, effectiveness, or manufacturing quality

The compounded versions appeal primarily to people without insurance coverage who find brand-name prices prohibitive