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A retrospective, population-based cohort study found that treatment with glucagon-like peptide-1 (GLP-1) receptor agonists was safe and associated with lower risks of cardiovascular or psychiatric comorbidities and lower mortality among patients with psoriasis

doi: 10.1056/NEJMoa2307563 [DOI] [PubMed] [Google Scholar] 200

These may include: Regulatory Challenges: The GLP-1 Receptor Agonist Market faces significant regulatory challenges that can impede product approvals and market entry

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25 , 52 Following PD-1/PD-L1 inhibitor resistance, Tregs proliferate in the TME, increasing CTLA-4 expression and inhibiting DC co-stimulation of CD8 + T cells via CD80/CD86 binding