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15 At Lonza Capsugel, our scientists partner with you to design oral delivery strategies that address the core challenges of biologic drug delivery instability, permeability, and site-specific uptake with the goal of enabling clinically and commercially viable oral dosage forms

GLP-1 receptors in the brain, CGRP reduction, neuroinflammation suppression, intracranial pressure reduction, these all point in the same direction

The interpretation of these findings is confounded by the low number of dementia cases in each study

This increase was associated with a 1.5-fold increase in portal plasma GLP-1 upon gastric glucose stimulation in diet-induced obese VSG rats compared to diet-induced obese sham controls, suggesting that antral GLP-1 producing cells contribute significantly to portal GLP-1 (Ribeiro-Parenti et al., 2021)