pooping on tirzepatide and Mucus in Stool: Causes and When to Seek Care Tirzepatide and Bowel Movements: Managing
Description
Diabetes & Endocrinology, 11 (1), 3341

Really long compared to most medications

Because tirzepatide's half-life is slightly shorter, it clears marginally faster than semaglutide in the reverse direction, but this does not meaningfully change the washout guidance for sema-to-tirz switching

Withholding information about conditions like pancreatitis, thyroid cancer, or multiple endocrine neoplasia type 2 could put your safety at risk

The SURMOUNT-1 trial demonstrated significant weight loss, with patients losing approximately 15-21% of their body weight at the 15 mg dose over 72 weeks, depending on the statistical method used
