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Of course we have new technology to do it too, but really shifted to biologics, the complex proteins that are harder to manufacture

In patients with comorbid coronary artery disease, obesity, and diabetes, GLP-1 agonists and SGLT-2 inhibitors should be used as first-line agents, over metformin

It is licensed for type 2 diabetes

If the above measures are not as efficient as expected, either a decrease in GLP-1 RA dose or a temporary interruption of the treatment may be considered [35]