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To investigate the relative contribution of non-genetic factors that predict GLP1 medication efficacy, we fit a linear model to assess the combined effect of age, sex, pre-treatment BMI, drug type, drug dose and time on drug on total BMI loss (Supplementary Table 3)

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Once you settle in at your maintenance dose, gastrointestinal side effects should improve and ultimately go away (although for some people, you may feel mild side effects the day after you give yourself the injection)

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