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In this observational study, greater weight-loss efficacy did not necessarily translate into more favorable body-composition outcomes, underscoring the need for clinical decision-making and trial designs that maximize each patients likelihood of achieving a Prime GLP-1 metabotype

GLP-1 receptor agonists (semaglutide, liraglutide, tirzepatide) act on the brain as well as the gut, and a 2026 real-world cohort study from Kamel-Abusalha et a

Tirzepatide does not appear to increase cancer risk in humans, but caution is warranted due to animal studies showing thyroid C-cell tumors in rats, similar ...

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