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Description
Metformin, a biguanide anti-hyperglycemic agent, is the first-line treatment for type 2 diabetes (11)
stacking potent or erratic supplements raises the probability of adverse effects, undermines adherence, and confuses clinical decision-making when issues arise

Metabolic effects: For patients with type 2 diabetes, blood glucose levels typically begin rising as the medication's insulinotropic and glucagon-suppressing effects wane

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Small, frequent sips throughout the day may be better tolerated than large volumes at once, given the delayed gastric emptying associated with GLP-1 therapy
