retatrutide phase 2 nejm 2023 weight loss percent 48 weeks Tirzepatide as Compared with Semaglutide for the Treatment of Obesity Reta Weight Loss: Phase 3
Description
Additional benefits are expected from double and triple agonists, but specific human clinical trials are needed

Table 1 Clinical characteristics of the 44 obese stone formers followed longitudinally The GLP-based therapies used during the weight loss intervention included semaglutide (86%), tirzepatide (48%), liraglutide (21%), and dulaglutide (14%), with patients switching between these agents on the basis of insurance coverage and/or medication availability
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Liraglutide was administered to mice after suppression of the gut microbiota by antibiotics

(2015) 3:e00155
