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From study baseline to the end of follow-up, GLP-1RAs treatment resulted in statistically significant decreases in weight (MD=-2.32 kg, 95% CI: -4.21 to -0.43) and BMI (MD=-0.82 kg/m2, 95% CI: -1.47 to -0.17)

Higher maximum semaglutide dose was strongly associated with greater weight loss during the pre-landmark period (3.15% additional weight loss per 1mg increase

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