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Gler sees both sides as reason for deeper investigation

and Thompson, L.U., 2004

Although all of these are considered beneficial and protective mechanisms, there is still some debate about the frequent adverse effects (AE) they have, most of them of gastrointestinal nature (151, 152)

This impairment can lead to neuronal damage and increased A accumulation, a key feature of AD pathology [14, 15]
