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glp-1 agonist gastric emptying Agonist-Induced Delayed – A Clinical Pharmacology Perspective My thoughts exclusively --> PPIs
Description
GLP-1 also slows down the rate at which the stomach empties, which helps control appetite and food intake
doi: 10.1124/jpet.103.051987 89 DeYoungMBMacConellLSarinVTrautmannMHerbertP
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation
No evidence of increase in calcitonin concentrations or development of C-cell malignancy in response to liraglutide for up to 5 years in the LEADER trial
However, components of obesity pathology -particularly IR and low-grade inflammation- may impair these protective mechanisms, thereby contributing to the development of SO
