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compared with add-on, the rate of improvement in HbA1c at 12 months was modest in switch and reduce
Rosenstock J, Reusch J, Bush M, Yang F, Stewart M, Group for the AS

doi: 10.1161/jaha.119.015716
A meta-analysis in older adults found that HMB supplementation significantly increased muscle mass by 0.352 kg with no change in fat mass
