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While statistically significant, however, the clinical significance is questionable

Criteria for approval of GLP-1 medications: The medication is prescribed to reduce excess body weight and maintain weight reduction in combination with current and ongoing lifestyle modification including structured nutrition and physical activity

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Microarray and RNA-seq data generated in this study have been deposited in the Gene Expression Omnibus under accession code GSE184055 and GSE184261, respectively

2, indicating that the GLP-1RA group had a lower risk of MACEs during the follow-up period compared to the control group