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It said thats based on reports of those events observed with a variety of older medicines used or tested for weight loss. The agency said health-care professionals should still monitor patients for suicidal thoughts, signs of depression or any unusual mood changes.

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Rocket 1 was a 90-day efficacy trial that did not achieve its primary endpoint, but netarsudil did demonstrate noninferiority compared with timolol in subjects with IOP below 26 mmHg at all nine measured time points and numerical superiority over timolol at the majority of measured time points

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