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Key Takeaway: Dry mouth on Zepbound is typically caused by a combination of direct action on salivary gland receptors and a secondary effect of reduced fluid intake or metabolic water loss

Laurindo LF, Barbalho SM, Guiguer EL, da Silva Soares de Souza M, de Souza GA, Fidalgo TM, et al

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If you carry variants that reduce GLP-1 receptor sensitivity or increase fat storage predisposition, your provider may recommend tapering to a microdose or staying on low-dose therapy longerpersonalized guidance that reduces regain risk
