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Description
[1] [2] Key findings included: Participants receiving the highest dose (12 mg) achieved a mean weight reduction of approximately 17.5% of body weight at 24 weeks

One of the challenges with the new drugs is that preliminary findings indicate that adults need to remain on them long-term to sustain their weight loss, similar to many blood pressure and cholesterol medications

What I found was surprising

Semaglutide causes a steady, less intense feeling of nausea during dose escalation and after reaching a stable level

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