glp-1 agonists cardiovascular diseases Frontiers GLP-1 receptor agonists (GLP-1RAs): cardiovascular
Description
Two mechanisms of intestinal sympathetic nervous system activation by GLP-1RA must be considered: central nervous system-mediated effects and direct peripheral effects

10.1002/osp4.84 [DOI] [PMC free article] [PubMed] [Google Scholar] 37.Rosenstock J, Klaff LJ, Schwartz S, Northrup J, Holcombe JH, Wilhelm K, et al
The SMR analysis showed that increased GLP1R gene expression was associated with a reduced risk of anxiety, but no significant associations were observed with other mood disorder-related adverse reactions

This effect is what has made it so popular for weight management therapies, including Ozempic

And Then What
