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Description
Disadvantages of semaglutide include the fact that they are weekly injection (except the oral form, Rybelsus), higher costs, and side effects

Most people notice subtle changes but nothing dramatic
At week 64, participants taking the once-daily 25mg dose along with a reduced calorie diet and exercise achieved an average weight loss of 13.6 percent compared with 2.4 percent for placebo, with a greater effect (16.6 percent) in those fully compliant with therapy versus 2.7 percent with placebo

Of the 40 patients for whom data was available, 39 reported lost vision

Conclusion So just some concluding thoughts here
