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GLP-1 therapy isnt recommended for teens with certain medical conditions such as a personal or family history of medullary thyroid cancer or MEN2, pancreatitis, severe gastrointestinal issues (like gastroparesis or IBD flare), current or planned pregnancy, or active eating or psychiatric disorders

The risk of ketotic hyperglycemia did not increase in the aforementioned meta-analysis (56)

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These effects lead to reduced caloric intake and subsequent weight loss

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