who should not use a glp 1 GLP-1 Meds: What They Really Do and What They Don't GLP-1 has changed the conversation
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They were especially important in identifying cardiovascular effects such as increased heart rate, and assessing gastrointestinal tolerability
Strong pharmacovigilance, physician-led prescribing, patient education, and real-world evidence generation will be critical to sustain long-term trust in this therapeutic class

These drugs have also caused new or worsening kidney disease, including kidney failure, in some people
Safety and efficiency of dipeptidyl peptidase IV inhibitors in patients with diabetic kidney disease: A systematic review and meta-analysis

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