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The TRIUMPH Phase 3 program uses 9 mg and 12 mg as the primary therapeutic doses, with a 4 mg maintenance dose being explored for weight maintenance after initial loss

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Studies have found that tirzepatides hormone-secreting activities depend on GIPR, highlighting the critical role that GIPR plays in the medications mechanism of action and its therapeutic effects [19]

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10.1186/s12868-016-0272-9 BMC Neurosci
