glp 1 agonist review Mechanisms of action of GLP-1RA A clinician's perspective ๐ GLP-1
Description
Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor
Mechanistically, these effects are coherent
The mean follow-up on-treatment was 181 days (median 155 days, IQR 71 to 290 days) for tirzepatide initiators and 174 days (median 148 days, IQR 82 to 254 days) for semaglutide initiators
doi: 10.1002/jcb.22625
What mechanisms behind weight loss remain unclear
