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For the assessment of WOMAC pain subscale score, the potential confounders include obesity management medications, prohibited knee procedures and excessive use of pain rescue medication

GLP-1 affects: The brain (reduces hunger) The stomach (slows digestion) The pancreas (helps release insulin at the right time) The liver (reduces extra sugar release) Some people have a weaker GLP-1 response, which makes it harder to control hunger or feel satisfied after eating

Hypoglycaemia risk increases when Ozempic is combined with sulfonylureas or insulin, requiring dose adjustment of concomitant medications

Semaglutide is a GLP-1 receptor agonist that mimics natural gut hormones to reduce hunger, slow digestion, and improve insulin levels

Knowing that this is a documented, transient effect helps manage anxiety about the sensation