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Metformin (off-label for weight management) Metformin is the most widely prescribed diabetes medication in the world, and while it is not FDA-approved for weight loss, it consistently produces modest weight reduction of 2-5% in clinical studies

2020;31:11891205.e13

The method used in the study is not the gold standard scintigraphy that involves radioactive tracers, and the researchers did not take into account secretion-based error [40]

Development and Approved Uses Naltrexone Naltrexone was developed in 1984 for the treatment of opioid use disorder
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