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8 While the changes shown in Figure 1 were reversible within 2 h, an overall concern might be that if diabetics already had a slightly thicker cornea than normal, 5 then the extent of swelling of the cornea associated with contact lens wear would be even greater than in non-diabetic individuals resulting in unacceptably persistent corneal oedema

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Drug and Alcohol Dependence , 112424

Jastreboff et al., NEJM, 2022 (SURMOUNT-1) Dramatically Improves Metabolic Health Tirzepatide leads to significant improvements in blood sugar, insulin sensitivity, and cholesterol, powerfully addressing the metabolic dysfunction that drives aging

For example, LY3437943 , a novel triple agonist peptide discovered by Eli Lilly that targets the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and GLP-1R (GCGR+GIPR+GLP-1R from the list above), can effectively reduce body weight and improve glycemic control in obese mice