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The prevalence of low muscle mass associated with obesity in the USA
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Proper dosing schedules become essential because higher doses lead to more frequent side effects such as gastrointestinal upset, and the side effects can be managed by using the minimum effective dose or slow titration (Figure 2)
However, the SURPASS J-mono trial found that although HbA1c reductions increased with higher tirzepatide doses, differences in weight loss between 10 and 15 mg were modest, which is consistent with our observations [6]
Epidemiology and pathogenesis of ulcerative colitis
