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Id be very cautious about products like that, says Raj Dasgupta, MD , associate professor of clinical medicine at the University of California, Riverside School of Medicine

Discussion In the current systematic review and meta-analysis, 10 RCTs were analyzed to evaluate the effectiveness and safety of combination therapy with SGLT-2i and GLP-1RA compared to monotherapy of each individually on the incidence of MACE and hospitalization for heart failure

however, metformin initiation was associated with substantially higher levels of adherence

doi: 10.1016/j.cmet.2021.12.012

Liraglutide typically starts at a low dose (0.6 mg) and gradually increases to a maintenance dose based on your healthcare provider's guidance